Genetic ablation of fibroblast activation protein alpha attenuates left ventricular dilation after myocardial infarction
نویسندگان
چکیده
منابع مشابه
Giant left ventricular aneurysm after myocardial infarction.
a Cardiac Surgery Department, University Hospital of Salamanca, Salamanca, Spain b Internal Medicine Department, University Hospital ‘‘Marqués de Valdecilla’’, Santander, Spain c Internal Medicine Department, George Washington University School of Medicine, Washington DC , United States d Cardiovascular Surgery Department, University Hospital ‘‘Marqués de Valdecilla’’, Santander, Spain e Radiol...
متن کاملLeft Ventricular Size after Acute Myocardial Infarction
The distance from the midline to the left heart border measured in a standardized manner on calibrated chest roentgenograms was determined serially in 125 patients after acute myocardial infarction. This external left heart dimension (LHD) was compared to the normal value, and its prognostic value was assessed during early and late follow-up periods (average 10, range 2-31 months). Within 96 ho...
متن کاملLeft Ventricular Remodeling After Myocardial Infarction
Left ventricular remodeling is the process by which ventricular size, shape, and function are regulated by mechanical, neurohormonal, and genetic factors.1,2 Remodeling may be physiological and adaptive during normal growth or pathological due to myocardial infarction, cardiomyopathy, hypertension, or valvular heart disease (Figure 1). This article will review postinfarction remodeling, pathoph...
متن کامل[Left ventricular remodeling after myocardial infarction].
Left ventricular remodeling describes a number of geometric and structural changes that the left ventricle undergoes after myocardial infarction. Briefly, it comprises expansion of the infarct and dilatation of the healthy left ventricular segments. Its severity is related to the infarct size. These changes in ventricular geometry, in particular the dilatation, influence the long-term incidence...
متن کاملMyocardial Connective Tissue Growth Factor (CCN2/CTGF) Attenuates Left Ventricular Remodeling after Myocardial Infarction
AIMS Myocardial CCN2/CTGF is induced in heart failure of various etiologies. However, its role in the pathophysiology of left ventricular (LV) remodeling after myocardial infarction (MI) remains unresolved. The current study explores the role of CTGF in infarct healing and LV remodeling in an animal model and in patients admitted for acute ST-elevation MI. METHODS AND RESULTS Transgenic mice ...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2021
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0248196